Standardized CAR-T Detection Reagents for Global Flow Cytometry
Engineered antigen-based reagents for reproducible CAR-positive cell detection and optional receptor-density analysis.
- Batch-to-batch consistent
- Engineered for high precision
- Very low background
- Optional receptor density quantification
Used by scientists at leading hematology and cancer research institutions
BlueRay reagents are already being used by specialized laboratories and research groups across major academic and translational research environments.
Hematological Diagnostic Laboratory of Heidelberg University Hospital
DKFZ
German Cancer Research Center
University Hospital Erlangen
Cell-therapy and hematology research workflows
Heidelberg University
Translational Immunology research groups
More institutions and research groups are joining
Growing adoption across advanced translational research environments.
Hematological Diagnostic Laboratory of Heidelberg University Hospital
DKFZ
German Cancer Research Center
University Hospital Erlangen
Cell-therapy and hematology research workflows
Heidelberg University
Translational Immunology research groups
More institutions and research groups are joining
Growing adoption across advanced translational research environments.
How It Works
Quantitative CAR-T Measurement Principle
From engineered antigen binding to reproducible CAR expression readouts.
High-Specificity CAR Binding
Engineered antigen-based detection reagents bind CAR-specific structures with high sensitivity and specificity.
Very Low Background
Optimized Fc-region design and reagent configuration reduce non-specific binding and improve signal clarity.
Batch-to-Batch Consistency
Controlled manufacturing, strict quality control, and site-specific fluorochrome conjugation support consistent performance.
Optional Receptor Density Readout
SCOPE Cell Mimics support quantitative readouts, including Accessible CAR Molecules per cell.
CAR-T cell samples analyzed
Supporting robust assay development and analytical validation.
Precision Detection for CAR-T Cell Detection
Why Today's CAR-T Monitoring Falls Short
Current CAR-T flow cytometry workflows often force laboratories to choose between high-quality but expensive detection reagents, or lower-cost alternatives with limited validation, variable performance, and reduced comparability.
Affordable per-test workflow
Designed to support broader use across research groups and industry partners.
High cost per test
Premium detection reagents can limit routine monitoring and large-scale use.
Batch-consistent reagents
Controlled production, strict quality control, and defined conjugation ratios support reproducible staining.
Batch-to-batch variability
Lot-dependent differences, including fluorochrome configuration, can affect staining consistency.
Simplified one-step staining
Designed for standardized CAR-T measurement with comparable readouts across laboratories and instruments.
Lab-dependent protocols
Different gates, reagent formats, and workflows make cross-site comparison difficult.
Optional ACM readout
Supports CAR-positive percentage and optional Accessible CAR Molecules per cell quantification.
Limited quantitative calibration
Many workflows report CAR-positive percentages without standardized receptor-density information.
Products
Featured Detection Reagents
Ready-to-use reagents for CAR-T cell detection by flow cytometry
Technology
The SCOPE Technology Platform
A comprehensive approach to standardized CAR T cell detection and receptor-density quantification
SCOPE Detection Reagents
Antigen-based CAR detection reagents optimized for stable, reproducible staining, low background, and high specificity.
Learn moreSCOPE Reference Cell Mimics
Standardized reference materials designed to support assay consistency, workflow checks, and inter-lab comparability.
Learn moreSCOPE Certification
Coming soon: proficiency-style support for external quality assessment and consistent reporting.
Join early accessWhy Choose Us
Technical Advantages
Low Background & High Specificity
Robust performance with minimal non-specific binding.
Manufacturing Reproducibility
Optimized processes ensure batch-to-batch consistency.
Universal Flow Cytometry Compatibility
Works with standard flow cytometry platforms and workflows.
Quantitative CAR-T Analysis
Supports CAR-positive percentage and optional ACM readouts.